Abstract (provisional)
Background
Malignant pleural effusion (MPE) is an
extremely common problem affecting cancer patients, and thoracentesis is an
essential procedure in an attempt to delineate the etiology of the fluid
collections and to relieve symptoms in affected patients. One of the most
common complications of thoracentesis is pneumothorax, which has been reported
to occur in 20% to 39% of thoracenteses, with 15% to 50% of patients with
pneumothorax requiring tube thoracostomy.
The present study was carried out to assess
whether thoracenteses in cancer patients performed with ultrasound (US)
guidance are associated with a lower rates of pneumothorax and tube
thoracostomy than those performed without US guidance.
Methods
A total of 445 patients were recruited in
this retrospective study. The medical records of 445 consecutive patients with
cancer and MPE evaluable for this study, undergoing thoracentesis at the
Oncology-Hematology and Internal Medicine Departments, Piacenza Hospital
(Italy) were reviewed.
Results
From January 2005 to December 2011, in 310
patients (69.66%) thoracentesis was performed with US guidance and in 135
(30.34%) without it. On post-thoracentesis imaging performed in all these
cases, 15 pneumothoraces (3.37%) were found; three of them (20%) required tube
thoracostomy. Pneumothorax occurred in three out of 310 procedures (0.97%)
performed with US guidance and in 12 of 135 procedures (8.89%) performed
without it (P <0 .0001="">0>
Conclusions
The routine use of US guidance during
thoracentesis drastically reduces the rate of pneumothorax and tube
thoracostomy in oncological patients, thus improving safety as demonstrated in
this study.
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