UGAP measurements
UGAP measurements were performed using a
LOGIQ E10 ultrasound machine (GE Healthcare, Wauwatosa, WI, USA), using a C1-6-D convex array probe.
All measurements were performed in fasting conditions
for more than 4 hours, on patients in a supine position,
with the right arm in maximum abduction, by intercostal
approach, in the right liver lobe. A large colored-coded
attenuation map, automatically adjusted by the system,
was positioned in the right liver lobe, in a homogenous
area of the liver, free of large vessels (fig1). Using the
quality map option, the best image was selected in order
to acquire the attenuation coefficient measurement. Ten
measurements were performed using one or two selected
images of the liver and the values were automatically
stored in the system. Reliable UGAP measurements were
defined as the median value of 10measurements performed in a homogeneous area of liver parenchyma, with
an IQR/M <0.30. UGAP values are expressed in dB/cm/
MHz or in dB/m.
LOGIQ E10 ultrasound machine can also perform
liver stiffness measurements for fibrosis evaluation using an accurate 2D-Shear Wave Elastography (2D-SWE)
technique [20-23], but this type of evaluation was not included in the present study.
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